Wataƙila kun taɓa jin labarin rashin lafiyar chromosomal, musamman idan a cikin yanayinku na kusa akwai takamaiman lamarin, zaku san abin da yake game da mafi daidaito.
Amma idan baku taba sanin shari'ar wani ba mutumin da yake da matsalar rashin lafiyar chromosomal ko kuma baku taɓa sanar da kanku game da shi ba, to zai zama da kyau ku ci gaba da karantawa.
Matsalolin chromosomal
Abun rashin dacewar chromosomal sune waɗanda ke faruwa sakamakon rashin daidaito a cikin chromosomes yayin ciki na tayi. Idan ƙwayoyin ƙwayoyin cuta (ovum ko sperm) suka ƙunshi kuskure a cikin bayanansu, maye gurbi zai kasance a cikin dukkanin ƙwayoyin jikin da aka samar daga haɗuwar waɗannan gametes. Maye gurbi shine, to, gado ne kuma ana yada shi daga tsara zuwa tsara.
Wadannan rashin daidaito na chromosomal iri biyu ne: Za su iya zama canje-canje a cikin yawan chromosomes ko canje-canjen tsarin a cikin chromosomes. A na farko, sanannen cuta kuma mafi saurin yaduwa shine trisomy na chromosome 21 ko Down syndrome da sauran masu saurin kamala kamar trisomy na chromosome 18 ko Edwards syndrome, trisomy of chromosome 13 ko Patau syndrome.
Kuma dangane da canjin tsarin chromosome, illolin na iya zama da bambamcin gaske: daga cutuka masu haɗari da ƙanana don rashin kawo matsala. Daga cikin cututtukan da muka fi sani muna nunawa: Cutar Cutar Meow, Cutar Prader-Willi ko Ciwan Angelman, da sauransu. Nan gaba zamu ga wannan batun gaba daya dalla-dalla.
Menene chromosome?
Chromosomes tsaruka ne wadanda suke dauke da kwayar halittar mutane. Kwayoyin halitta sune umarnin mutum daya wanda yake fadawa jikin mu yadda ya kamata ya bunkasa da kuma ayyukan da ya kamata ya bi. Chromosomes suna kula da halaye na jiki da na likita, sune wadanda suke ayyana launin gashi, nau'in, nau'in jini ko kuma idan mutum zai kasance mai rauni ko rashin lafiya.
Yawancin chromosomes suna da sassa biyu da aka sani da makamai waɗanda suka rabu, ana kiran ɗan gajeriyar "p" kuma mafi tsayi "q" Jiki ya kunshi kowane bangare ana kiransa sel, akwai nau'ikan sel daban-daban (fata, hanta, jini ...) kuma dukkan kwayoyin halitta suna da wani tsari da ake kira tsakiya, a tsakiyan tsakiya inda ake samun kwayoyin.
Chromosom nawa muke da su?
Adadin yawan chromosomes a jikin mutum shine 46, kuma akwai nau'i-nau'i 23 tare da kimanin jimillar kwayoyin 20.000 ko 25.000. Saiti daya na chromosomes 23 ana gado ne daga kwan mahaifiya sannan sauran kwayoyin chromosomes ana gado ne daga maniyyin mahaifin.
Daga cikin wadannan nau'ikan chromosomes 23, na farko 22 ana kiransu "autosomes" kuma na karshe sune "chromosomes na jima'i." Jima'i chromosomes yana ƙayyade jima'i a cikin mutum, mata suna da chromosomes x biyu (XX) kuma maza suna da chromosome X ɗaya da Y chromosome ɗaya (XY). Uwa da uba suna ba da gudummawa ga saitin motocin 22 da chromosome na jima'i.
Matsalolin chromosomal
Akwai nau'o'in rashin daidaito na chromosomal, duk da haka, a halin yanzu, ana iya tsara su kamar yadda na ambata a sama zuwa ƙungiyoyi biyu na asali: rashin daidaituwa na lamba da rashin tsari.
Lambobin lambobi
A cikin rashin dacewar lambobi, mutum ya rasa ɗayan chromosomes na ma'aurata, wani abu da an san shi da monosomy. Lokacin da mutum yake da chromosomes fiye da biyu maimakon biyu, ana kiran yanayin trisomy.
Kamar yadda na ambata a farkon wannan labarin, misalin lambobin adadi zai zama Down Syndrome, wanda ke tattare da raunin hankali, matsalolin ilmantarwa, yanayin fasalin fuskar mutum, ƙarancin tsoka a yarinta, yaren da ya saba na al'ada, da sauransu. . Mutumin da ke fama da ciwo yana da kwafi uku na chromosome 21 maimakon biyu, saboda wannan dalilin ana kiran wannan yanayin Trisomy 21.
Wani misali na monosomy wanda mutum baya da chromosome shine Turner Syndrome. A cikin wannan ciwo, yawanci ana haihuwar mace tare da chromosome na jima'i, na X kuma yawanci ya fi ƙasa da na al'ada don haka ba za ta iya samun yara tsakanin sauran matsalolin ba.
Abubuwa marasa tsari
A cikin waɗannan rikice-rikicen tsarin chromosome za a iya canza shi ta hanyoyi da yawa, misali:
- Sharewa: wani ɓangare na chromosome ya ɓace ko an share shi.
- Kwafin abubuwa: wani ɓangare na chromosome an maimaita saboda haka akwai ƙarin kayan halittar gado.
- Canje-canje: wani bangare na chromosome an canza shi zuwa wani chromosome, akwai manyan nau'ikan juzu'i biyu: juyawa da kuma sauyawar Robertsonian. A wani canjin canjin yanayi an yi musayar bangarorin chromosomes daban-daban. Kuma a cikin sauyawar Robertsonian, cikakkiyar chromosome ta haɗu da wani a rabewar hannayen chromosome (centrometer).
- Zuba jari: wani sashi na chromosome ya zama ware ko a haɗe, wani abu da zai haifar da juya kwayoyin halittar.
- Zobba: wani sashi na chromosome ya balle kuma ya samar da da'ira ko zobe, wannan na iya faruwa tare da asara ko ba tare da asarar kwayoyin halittar ba.
Me yasa cututtukan chromosomal suke faruwa
Yawancin cututtukan chromosomal suna faruwa ne saboda wata matsala takan faru ne da kwan ko maniyyi a lokacin hadi ko bayan kwan kwan. Lokacin da matsalar ta faru a cikin ƙwai ko maniyyi, lahani zai kasance a kowane sel na jiki. Amma wasu abubuwan rashin al'aura, duk da haka, suna faruwa bayan ɗaukar ciki don haka wasu ƙwayoyin na iya zama marasa kyau wasu kuma bazai yiwu ba.
Rashin lafiyar cututtukan ƙwayoyin cuta na iya gado daga iyaye ko sabon abu ga mutum. Wannan shine dalilin da ya sa lokacin da aka haifi yaro da mummunan yanayi, yawanci ana yin karatun chromosome ne akan iyayen.
Abubuwa marasa kyau na chromosome gabaɗaya suna faruwa yayin da aka sami kuskure a cikin rabewar sel. Akwai rabe-raben salula iri biyu, mitosis (kwayoyin biyu kwafi ne na kwayar asali) da meiosis (kwayoyin dake da rabin adadin chromosomes, 23 maimakon 46). Hakanan akwai wasu abubuwan da ke haifar da haɗarin cututtukan chromosomal, kamar shekarun uwaye.
hello Na karanta duk labaran ku akan binciken chromosome kuma ina son su ina da ciki na trisonomy 18 kuma sun tsayar da ciki na a watanni 6 da suka gabata wato shekara daya kenan ina son sake samun ciki amma ina farin ciki da cewa abu ɗaya ne faruwa da ni ya kamata in yi ko wane gwaji ya kamata in yi don sanin ...
nemi likita
Barka dai, ni goggon melani ce wacce ke fama da canjin chromosome.Binchotogenetic shine 45, xx, dec (15; 18) (p11.2; p11.2) ish dec (15; 18) (p11.2; p11.2) . 1521) (d1821 +, snrpn +, pml +, d20 +) (XNUMX) Wani zai iya taimaka mana kuma ya faɗi abin da duk wannan yake nufi tunda masanin halittar gado kawai ya basu sakamakon ba tare da bayyana komai ba kuma taron na gaba yana dashi shekara mai zuwa. tunda nayi musu godiya kuma ina fatan zaku iya taimaka mana
NA JI CEWA AKWAI WATA SADUWA A CIKIN SOSHIN DA BATA IYA SAMUN RA'AYI A SAHUN RA'AYI. MUTUM ZAI IYA JAGORAN RAYUWAR TA'ADDA KUMA BABU WANDA YA FAHIMTA AMMA YANZU XYY YAYI ZALUNCI. TA YAYA ZA KA SANI? KA IYA TAIMAKA MIN
Ina da ciki amma amfrayo bai girma ba kuma zuciyarta ba ta buga ba, ina da makonni 10 kuma na fara zub da jini, sun yi magani kuma sun yi nazarin abin da suka fitar kuma hakan ya haifar da canje-canjen chromosomal, Ina jin tsoron samun mai juna biyu kuma, abu daya zai iya faruwa kuma?
Na gode, Ina fatan amsarku,
Ina fatan za ku iya taimaka min ina da shekara 25 kuma na yi ciki biyu, daya an hada shi wani kuma da cututtukan chromosomal, duk na rasa su a makonni 6. Shekaru 1 kenan kenan da yin hakan kuma ina son yin ciki amma ina tsoron faruwar hakan
hello ina da ciki makonni 13. Amma amfrayo yana raye ne kawai har zuwa sati na 9. Lokacin da na fara zubar jini a sati na 13 na samun ciki, na sami magani kuma likitan mata ya ce zubar da cikin ne aka rasa. Me yasa wannan ya faru, idan har zan iya samun yara na al'ada?
Na gode sosai Ina fatan za ku iya taimaka min.
awww
Ina bukatan cututtukan chromosomal guda 10 don aikin gida! za'a iya taya ni??
kyakkyawan aiki amma dole ne su buga sunan marubucin
hello 'yata tana da canjin chromosome cewa wannan bhoy kamar babu wani wanda yake da ita shine bangarancin chromosome 15 wani bangare na trisomy chromosome 5
SANNU, NA SAMU ZUBE GUDA BIYU, SANNAN CIKIN CIKI WANDA INA DA YARINYAR MAGANA, SANNAN SAURAN CIKIN. SANNAN NAYI CIKI CIKI, MENENE HUJJAR SAMUN SABON JARI?
Sannu a gare ni, ciki na makonni 12 kwanaki 4 ya tsayar da ni, na yi duban dan tayi tare da ma'aunin TN kwanakin da suka gabata kuma komai ya yi daidai, lokacin da na sami maganin sai aka ce jaririn ba shi da nakasa kuma sakamakon ya yi daidai da canje-canjen chromosomal .
Ina so in san abin da wannan ke nufi kuma saboda kawai ya tsaya a kusan makonni 13, na riga na kasance makonni 15 lokacin da nake da warkarwa.
Muchas Gracias
Shin wani zai iya gaya min cewa canjin chromosome biyu zai iya faruwa, menene haɗarin da wannan chromosome ya kawo ??? .. Zan yi matuƙar farin ciki idan wani zai iya gaya mani inda zan sami wani abu da ya shafi wannan 8 na chromosome ko abin da suka sani game da shi
Barka dai !!
Ina son sanin dalilin da yasa wadannan canje-canjen suke faruwa?
Barka dai, ina bukatan ku taimaka min, shekaruna 25 ne kuma na sami ciki biyu, na farko duk ya zama na al'ada kuma na rasa shi a sati arba'in hade da kwana 4, har yanzu ban san dalili ba kuma wani ya Na rasa shi a makonni 9. Ina da magani kuma na binciki abin da suka fitar kuma ya kasance tare da canje-canjen chromosomal, ina cewa canje-canje saboda na sami chromosomes 69 kuma abin da yake na al'ada 46 Ina jin tsoron sake samun ciki, shin abu ɗaya zai iya faruwa kuma?
Me yasa sauyin chromosomal yake faruwa ?????
Ina bukatan taimako …… .. Ina da yaro dan shekara 5, shekara daya da ta wuce na zubar da ciki yanzu na sake samun ciki kuma na sake rasa jaririn, sun ba ni embryoscopy kuma sun ce min na samu canji a chromosome 13, zai kasance zan iya sake gwadawa, zai kasance idan na sake samun juna biyu zai iya sake faruwa da ni ………. Da fatan za a taimake ni ……… Na gode.
Yanzu na yi farin ciki cewa na fahimci daga wannan shafin daidai bayanin da nake so!
Barka dai, na rasa juna biyu a cikin makonni 6 ko 7 inda ba a taɓa ganin amfrayo tare da amsa kuwwa ba, idan na san sun kasance ta hanyar amsa kuwwa. Mun yi binciken ne don ganin idan akwai canje-canjen chromosomal kuma muna jiran sakamako. Masanin kwayar halittata ya gaya mani cewa idan karatun ba daidai ba ne, ba zai warke ba, amma abin bakin ciki ne a sani! Ya Allah na! Za a iya ba ni bayani?
Makon da ya gabata na rasa jariri na a cikin makonni 11 na ciki, likitoci sun bayyana mani cewa dalilin ya samo asali ne daga canji a cikin chromosomes, kuma har zuwa yanzu da na karanta wannan labarin zan iya fahimtarsa, ba ya daina ciwo, duk da haka yanzu na fahimci dalilai kuma zan iya daina jin daɗin abin da ya faru.
Runguma Lupita <3 Kuma godiya ga yin tsokaci.
Barka dai. Shekaruna 21 da haihuwa kuma zaku ga cewa ina da juna biyu kuma ina son sanin ko saboda canjin halittar chromosomal
Barka dai Stacy, ya kamata ka nemi shawarar likitanka. Duk mafi kyau.