Jariri da aka haifa ya fito ne daga mahalli marasa tsabta amma, yayin da yake ratsawa ta mashigar haihuwa kuma yana saduwa da waje, zai fara zama mai mulkin mallaka ta ƙananan ƙwayoyin cuta waɗanda da sannu-sannu zasu zama microbiota ko flora ɗin hanji. Wannan kwayar halittar tana da matukar mahimmanci tunda bambancinsu da ayyukan su galibi sun dogara ne akan lafiya a duk rayuwar ta. Kwayoyin cuta da ke cikin hanji suna da alaƙa da ci gaban garkuwar jiki, suna kariya daga cututtukan hanji, cututtuka da cututtuka daban-daban.
Microbiota ba iri daya bane a duk jariran da aka haifa. Wannan ya bambanta dangane da nau'in haihuwa (bangaren farji ko na haihuwa), nau'in ciyarwa (shayarwa ko kwalba), makonnin ciki, magani na uwa ko jariri, da dai sauransu.
A cikin binciken da wani masanin kimiyya ya yi daga Babban Majalisar don Nazarin Kimiyya (CSIC), an yi nazarin su illolin gudanarwar maganin rigakafi yayin haihuwa akan microbiota na hanji na jarirai masu haihuwa cikakke. Sakamakon ya nuna cewa wannan aikin gama gari na yau da kullun na iya tallafawa mulkin mallaka ta hanyar ƙwayoyin cuta masu ɗauke da ƙwayoyin cuta waɗanda ke ɗauke da ƙwayoyin cuta don juriya da waɗannan maganin rigakafin.
Gudanar da maganin rigakafi ga uwa yayin haihuwa al'ada ce da ta zama gama gari (kusan kashi 30% na al'amuran). Ana amfani dashi azaman maganin rigakafi lokacin da mahaifiya ta tabbata a cikin binciken streptococcus, wani nau'in ƙwayoyin cuta wanda baya haifar da lalacewa a ƙarƙashin yanayin al'ada amma cewa, idan ya isa huhu, na iya haifar da mummunan sakamako ga jariri. A cikin karatun da ya gabata, an riga an gani cewa gudanar da maganin rigakafi ya haifar da canje-canje a cikin kwayar microbiota na jariran da ba su kai haihuwa ba. Bayan binciken da aka yi kwanan nan, an ba da waɗannan sakamakon ga yara masu cikakken iko. A cewar Miguel Gueimonde, daya daga cikin masu binciken CSIC, tasirin maganin rigakafi akan cututtukan fuka na hanji da yiwuwar bayyanar kwayoyin cuta masu ɗauke da ƙwayoyin halitta masu juriya sun cancanci kulawa ta musamman.
Kungiyar masu binciken, gami da masana kimiyya daga Babban Asibitin Asibitin Asturias da na Jami'ar Parma (Italia), sun yi nazari Samfura daga cikin yara 40 masu cikakken lokaci ta hanyar haihuwa ta farji. Daga cikin waɗannan, an haife 18 a cikin haihuwa inda aka yi amfani da mahaifiyar penicillin azaman maganin rigakafin rigakafi.
An bi diddigin yayin watanni ukun farko na rayuwar jarirai kuma, tare da sauran sakamako, a raguwar kwayoyin cuta na iyali Bifidobacteria wanda kasancewar sa yana da amfani ga jiki. Hakanan, an lura da ƙaruwa cikin ƙwayoyin cuta masu haɗari da juriya na Campylobacter ko Helicobacter genera.
A cewar masu binciken, binciken ba ya neman kawo karshen aikin bayar da maganin rigakafi, amma don yin gargadi game da illolin na biyu da kuma kafa harsashin kafa dabarun da nufin gyara wadannan canje-canjen, fifita mulkin mallaka da kafa kwayar halittar microbiota na hanji.