Njengoko nganye UDisemba 21 namhlanje lusuku lukaZwelonke loMntwana onomhlaza. Eli nyathelo lazalwa likhuthazwe yiSpanish Federation yaBazali baBantwana abaNomhlaza. E-Spain, umhlaza wabantwana uchaphazela malunga ne-1.100 yabantwana ngonyaka. Iindaba ezimnandi zezokuba ukusweleka komhlaza wabantwana kusezantsi. Nazi amazinga okusinda emva kweminyaka emi-5 yonyango kufutshane nama-80%, kwaye ifikelele kwi-100% kwezinye iintlobo ezithile zamathumba.
Ezi datha zinikezelwe liBhunga Jikelele leeKholeji zoMayeza, elipapashwe kuxwebhu lwalo Inqaku lezeMpilo 148. Ingxelo ivavanya imiba yezonyango kunye nonyango lweeoplasms eziqhelekileyo kubantwana, ukongeza ekuhlaziyweni kwendima yokhathalelo lwempilo yengcali yamayeza.
Indima yekhemesti kunyango lomhlaza wabantwana
Indima yekhemesti yile inegalelo kumgangatho wobomi obungcono kwaba baguli. Usokhemesti wenza igalelo kwimfundo yezigulana ezingabantwana kwaye iintsapho zenu kunye ne-leukemias kunye ne-lymphomas kwimiba efana nokutya, kuba unyango oluthile kunye nesifo ngokwaso kunokubangela ukungondleki. Izidumba zeHematological kunye nezo zenkqubo ye-nervous system zezona zixhaphake kakhulu malunga nomhlaza wabantwana. Malunga neepesenti ezingama-50 zabantwana abangaphantsi kweminyaka eli-15 ubudala abanomhlaza bane-leukemia.
Ekufumaneni kwangoko, usokhemesti liqabane, kuba ukuqala kweleukemia kunye nonyango lwe-lymphoma kuthathe isigqibo. Ezinye ze iiflegi ezibomvu ezinokubonwa ngusokhemesti Zezi: umkhuhlane wemvelaphi engaziwayo, ukunciphisa umzimba okanye ukuphawula i-asthenia kungekho sizathu sibonakalayo, ukugruzuka ngaphandle kwesizathu esichongiweyo, ukudumba kwe-lymph node, okanye ukubonakala "kwamaqhuma" ...
Bayanceda ukunciphisa umngcipheko wosulelo, Ukugxininisa kumanyathelo afana nokuhlamba izandla, ukuhambisa amanzi, ukwenza umthambo rhoqo kunye nokumodareyitha kunye nokuphepha izihlwele kwiindawo ezivaliweyo. Ngexesha lokwenza unyango, njengoko kusetyenziswa iziyobisi ezahlukeneyo, umsebenzi wosokhemesti kubalulekile ukwenza ukulandelela kunye nokujonga amayeza, ngakumbi ngokubhekisele kunyango lweCAR-T.
Unyango lwe-CAR-T, phambili kunyango lomhlaza wabantwana
Ukuvela kwento ebizwa ngokuba lunyango lwe-CAR-T kunyango lwee-leukemi kunye nee-lymphomas zihlala ziqhelekile. Olu hlobo lonyango, ngenxa yokuntsokotha kwalo, lwenza ukuba lubaluleke Intsebenziswano phakathi kwekhemesti yasesibhedlele kunye nekhemesti yoluntuUkuphucula ulawulo lweklinikhi kunye nokuqhubekeka kokhathalelo lwabantwana.
Uphando kwicandelo le-oncology, kwaye ngakumbi kwi-oncology yabantwana, ivelisa inkqubela phambili ebalulekileyo. U-LUnyango lwe-CAR-T luhlobo lwe-immunotherapy esetyenzisiweyo esekwe kutshintsho lwe-lymphocyte. Ezi ziiseli ezinoxanduva lokulawula ukuphendula komzimba. Injongo kukuba bakwazi ukubona iiseli zomhlaza njengezangaphandle kunye nokuzitshabalalisa.
ESpeyin Amaziko okuqala okukhuthaza esi sicwangciso kwizigulana zabantwana yayiyiKlinikhi yaseSibhedlele neSant Joan de Déu e Barcelona. NgoJuni 2020, isibhedlele seYunivesithi yaseLa Paz, sisebenzisa i-Pediatric Hemato-Oncology Service, saxela ukuba sikhuphe isigulana sokuqala esanyangwa kuLuntu lwaseMadrid ngeeseli zeCAR-T, inkwenkwana eneminyaka eli-11 ubudala.
Izicelo kwinkonzo yeentsapho
USilvana Briones, umfundi kwiDyunivesithi ezimeleyo yaseMadrid (UAM) ufumene isifundi sokuphuhlisa iprojekthi yokubambisana yokwazisa malunga nomhlaza wobuntwana kunye nolutsha, kubandakanya uncedo lwengqondo kwabo banengxaki kulo. Imalunga ne isicelo seMi RiquezAPP. Olu luvo lunembewu yalo kwiprojekthi yaseRiqueza de Vivir, eqhutywa nguMbutho weAragon waBantwana abanomhlaza.
Inyathelo lokuqala likaSilvana Briones, umfundi webhayoloji, ebengomnye wabaphumelele kwisayensi yeFord College Community Challenge Sponsor science. Isicelo siya kubonelela ngomxholo womdla malunga nomhlaza wobuntwana, ubungqina kwizigulana nakwiintsapho. Ukongeza, inecandelo lesayensi kunye nodliwanondlebe nabaphandi. Ngayo ufikelela uthungelwano lwamavolontiya abonelela ngenkxaso ekhethekileyo kwizigulana nakwiintsapho zabo.
Los Izibonelelo zesicelo sobumbano ziya kuhamba ngokupheleleyo kwimibutho yezigulana ezinomhlaza. Ngokwomphuhlisi wombono, injongo kukubonelela ngenkonzo yoncedo lwengqondo, enenkxaso yaBantwana abaneCancer Foundation.