La preeclampsia kusengenye ye izinkinga zokukhulelwa ezesatshwa kakhulu ngenxa yamandla ayo okufaka impilo kamama nengane engozini emahoreni ambalwa. Kunokuba yinkinga engavamile, iyisifo esiyinkimbinkimbi esishiya uphawu lwesikhathi eside empilweni yabesifazane yenhliziyo nemithambo yegazi kanye nezinso, futhi singathinta ngisho nempilo yenhliziyo yezingane zabo lapho sezikhulile.
Eminyakeni yamuva nje, kube nomkhuba okhulayo. inqubekelaphambili ebalulekile kokubili ekuqondeni izimbangela ze-preeclampsia kanye nokuvimbela nokwelapha kwayo. Kusukela kumadivayisi amasha okuhlola ahlunga amaprotheni ayingozi egazini likamama, kuya izinhlelo zesibhedlela eSpain Njengoba kugxilwe ekuhlolweni kwasekuqaleni nasekulandelelweni kulokho okubizwa ngokuthi "i-fourth trimester", indlela yokusingatha lesi sifo iyashintsha kakhulu.
Iyini i-preeclampsia futhi kungani iyingozi kangaka?
I-Preeclampsia ichazwa njengesifo esingapheli isifo somfutho wegazi ophakeme sokukhulelwa Kubonakala kusukela emavikini angama-20 okukhulelwa noma ezinsukwini ezimbalwa zokuqala ngemuva kokubeletha futhi akubandakanyi nje kuphela umfutho wegazi ophakeme kodwa futhi nomonakalo ezithweni ezahlukene zomzimba. Namuhla kubhekwa njengesifo sezitho eziningi lapho i-placenta ingasebenzi kahle futhi ibangela uchungechunge lwezinguquko emzimbeni kamama.
Kunokuba kukhawulelwe ekubeni "nomfutho wegazi ophakeme", kungathinta ngasikhathi sinye izinso, isibindi, ubuchopho, amaphaphu kanye nohlelo lokujiya kwegazi. Lokhu kuphazamiseka kokujikeleza kwegazi kuchaza ukuthi kungani, uma kungatholakali futhi kungaphathwa kahle, isimo singaba sibi kakhulu ngokushesha okukhulu futhi siholele ezinkingeni ezinkulu ezifana ne-eclampsia (ukuquleka), i-HELLP syndrome, isifo sohlangothi, ukwehluleka kwezinso okulimazayo noma ukuqhekeka kwe-placenta.
Ngokuphathelene nengane, i-preeclampsia ihlotshaniswa nokukhulelwa. umkhawulo wokukhula kwe-intrauterineUkuzalwa ngaphambi kwesikhathi kakhulu, futhi ezimweni ezimbi kakhulu, ukufa kombungu. Emhlabeni jikelele, kulinganiselwa ukuthi lesi sifo kanye nezinkinga zaso kubangela amashumi ezinkulungwane zokufa komama minyaka yonke kanye namakhulu ezinkulungwane zokufa ngaphambi kokubeletha, okunomthelela omkhulu kakhulu emazweni anengeniso ephansi nephakathi.
EYurophu naseSpain, yize izinhlelo zokunakekelwa kwempilo zivumela ukuqapha ngokucophelela ukukhulelwa, i-preeclampsia, kanye nokopha kwegazi, kusalokhu kuyinkathazo enkulu. esinye sezimbangela eziphambili zokufa komamaKuthinta cishe phakathi kuka-2% no-6% wabesifazane abakhulelwe, okuyisibalo esingabalulekile ngokwempilo yomphakathi.
Indlela eqala ngayo: indima ye-placenta kanye neprotheni ye-sFlt-1
Umbono wamanje we-preeclampsia ubeka placentaKwezinye izimo zokukhulelwa, ukuzivumelanisa kwenhliziyo kukamama nohlelo lwenhliziyo akwanele ngokuphelele, futhi igazi alifinyeleli ku-placenta ngokugeleza okwanele. Lokhu kugeleza okunganele kubangela ukungasebenzi kahle kwe-placenta, okuthi, nakho, kukhiphe izinto egazini likamama ezingalimaza i-endothelium (ulwelwesi lwangaphakathi lwemithambo yegazi) futhi kubangele impendulo yokuvuvukala nomfutho wegazi ophakeme.
Phakathi kwalezi zinto, iphrotheni eyodwa ivelele ebizwa ngokuthi i-sFlt-1I-sFlt-1, ekhiqizwa yi-placenta futhi eyaziwa ngekhono layo lokushintsha ubuqotho bemithambo yegazi, iyisici esibalulekile se-molecule ye-sFlt-1. I-sFlt-1 eyengeziwe ivimba izinto ezivikela i-endothelium, ikhuthaza umfutho wegazi ophakeme kanye nomonakalo wezitho zomzimba. Le molekyuli isibe yinto ebalulekile ekuxilongweni nasekucwaningweni kwezindlela ezintsha zokwelapha.
Umonakalo we-endothelial awugcini nje ngokuba khona ngesikhathi sokukhulelwa. Kunobufakazi obandayo bokuthi abesifazane abaye baba ne-preeclampsia basala benesifo sofuba. ingozi eyengeziwe yenhliziyo impilo yabo yonke: kulinganiselwa ukuthi bandisa kabili amathuba okuba nomfutho wegazi ophakeme ongapheli, bandise kane ingozi yokushaywa unhlangothi kanye nengozi yesifo senhliziyo esibangelwa yi-ischemic kathathu.
Lokhu kuxhumana nempilo yemithambo yegazi kuholele ekucabangeni ukukhulelwa njengohlobo oluthile lwesifo. "ukuhlolwa kokucindezeleka" kwesimiso senhliziyo sowesifazane. Uma kuvela izinkinga zomfutho wegazi ophakeme phakathi nalezo zinyanga, kuyisibonakaliso esiyisixwayiso okufanele sikhuthaze ukuqapha ngokucophelela eminyakeni elandelayo.
Izimpawu, izinhlobo zokwethulwa kanye nengozi kumama
Esinye sezici ezikhohlisayo kakhulu ze-preeclampsia ukuthi, ezimweni eziningi, ishintsha ngendlela yokuthi cishe kuthuleIphesenti elikhulu labesifazane aliboni lutho olungavamile, futhi ukuhlolwa kwegazi okuvamile kanye nokuhlolwa kwegazi kuphela okubona inkinga. Yingakho ochwepheshe begcizelela ukubaluleka kokungayeki ukuhlolwa kwangaphambi kokubeletha.
Uma kuvela izimpawu, lezi zingafaka phakathi ubuhlungu bekhanda obukhuluUkubona okufiphele noma okukhanyayo, ubuhlungu esiswini esingaphezulu (ikakhulukazi ohlangothini lwesokudla), isicanucanu nokuhlanza, ubunzima bokuphefumula, noma ukuvuvukala okubonakalayo kobuso nezandla. Ukuvuvukala okukhulu, ukukhuluphala ngokuzumayo, noma ubuthakathaka obujwayelekile kungadinga ukuhlolwa okuphuthumayo kwezokwelapha.
Uma isesimweni sayo esibi kakhulu, i-preeclampsia ingakhula ibe yi- i-eclampsiaLesi simo, esibonakala ngokuxhuzula, singaholela ekulimaleni kwezinzwa noma ekufeni. Singabangela futhi i-HELLP syndrome, lapho ukujiya kwegazi, ukusebenza kwesibindi, kanye nokukhiqizwa kwamaseli abomvu egazi kuthinteka khona konke, okuvame ukudinga ukuqedwa kokukhulelwa ngokushesha ukuze kuvikelwe umama.
Lesi simo siphoqa amaqembu odokotela bokubeletha ukuba enze izinqumo ezinzima, ikakhulukazi lapho lesi sifo sivela esemncane. Ngezinye izikhathi, ingozi yokwelula isikhathi sokukhulelwa okuyinkimbinkimbi kumama kumele ilinganiswe nokulimala kokukhulelwa isikhathi eside. ukuzalwa ngaphambi kwesikhathi kakhulu yengane. Umngcele phakathi kwesikhathi sokuthenga nokuthatha izingozi eziningi ubucayi futhi uhlolwa ngokwesimo ngasinye.
Izici zengozi: kusukela emlandweni womuntu siqu kuya ekudleni
Akubona bonke abesifazane abanamathuba afanayo okuthola i-preeclampsia. Kuyaziwa ukuthi ingozi iyanda uma kukhona... umlando we-preeclampsia Ingozi iphakeme ekukhulelweni kwangaphambilini noma uma owesifazane okhulelwe ene-hypertension engapheli, ukukhuluphala ngokweqile, isifo sikashukela, i-lupus, noma i-antiphospholipid syndrome. Iphakeme futhi ekukhulelweni okuningi nasekukhulelweni okutholakala ngobuchwepheshe bokusiza ekuzaleni.
Umthelela we imvelaphi yobuhlanga Kuye kwachazwa futhi, ngesifo esivame kakhulu futhi esibi kakhulu, kwabesifazane abamnyama. Kulezi zici kunezici zezenhlalo ezifana nezinga lokufinyelela ekunakekelweni kwangaphambi kokubeletha okuseqophelweni eliphezulu, okuphawula umehluko ocacile phakathi kwamazwe ngisho nangaphakathi kohlelo olufanayo lwezempilo.
Ngaphandle komlando wezokwelapha kanye nesizinda, ucwaningo lugxile ku- indlela yokuphila ngesikhathi sokukhulelwaUcwaningo oluhlanganiswe amaqembu avela eBarcelona (BCNatal, Hospital Clínic kanye ne-Institut de Recerca Sant Joan de Déu, phakathi kwabanye) luhlaziye abesifazane abakhulelwe abangaphezu kuka-800 ngaphakathi kocwaningo lwe-IMPACT BCN futhi luthole ubudlelwano obuphawulekayo phakathi kokusetshenziswa kokudla okucutshungulwe kakhulu engxenyeni yesibili yokukhulelwa kanye nengozi ye-preeclampsia.
Ngokusho kwedatha, kwandisa ukuba khona kokudla kwemikhiqizo efana iziphuzo ezinoshukela, amakhekhe acutshunguliwe noma ukudla okulungele Ukudla lokhu kudla phakathi kwezinyanga zesibili nezesithathu kuhlotshaniswa nengozi ephindwe kabili yokuthuthukisa lesi sifo. Esibonelweni esifundwe, lokhu kudla kumele cishe u-17% wama-calories adliwa nsuku zonke, okususa ukudla okusha kanye namaphethini okudla okunempilo.
Abalobi baveza ukuthi akuyona nje indlela yokudla ekuqaleni kokukhulelwa okubalulekile, kodwa kwenzeka kanjani Ukudla phakathi nezinyanga zonke. Abesifazane abakhulelwe abagcina noma abaqinisa indlela yokudla efana neyaseMedithera, ecebile ngemikhiqizo emisha, imifino, izithelo, ama-legumes, uwoyela womnqumo, nenhlanzi, babonakala bevikelekile kakhulu ezinkingeni zokubeletha, okuhlanganisa ne-preeclampsia.
Intuthuko ekwelapheni: isihlungi seprotheyini ye-sFlt-1
Okwamanje, okuwukuphela "kokwelapha" okuqinisekile kwe-preeclampsia kusasele ukuzalwa kwenganeOkusho ukuthi, ukususa i-placenta. Kodwa-ke, ukuhlinza noma ukwenza ukuhlinzwa ngaphambi kwesikhathi, ikakhulukazi ngaphambi kwamasonto angu-34, kunezingozi ezinkulu ezinganeni ezisanda kuzalwa, ezingadinga ukuhlala isikhathi eside ezindlini zokubeletha futhi zibhekane nezinkinga ezivamile zokukhulelwa ngaphambi kwesikhathi okukhulu.
Ngomgomo wokuthola izinsuku ezibalulekile zokukhulelwa ngaphandle kokubeka umama engozini, ithimba lamazwe ngamazwe eliholwa yiCedars-Sinai University of Health Sciences lisungule uhlelo lokuhlola ukukhulelwa. indlela entsha yokuhlola okushicilelwe kumagazini i-Nature Medicine. Le ndlela isekelwe ekususweni kwephrotheni ye-sFlt-1 egazini lowesifazane okhulelwe, enye yezimbangela eziyinhloko zokungasebenzi kahle kwe-endothelial okubonisa lesi sifo.
Abacwaningi baklame iphrotheni ekhethekile yokuzivikela yomzimba ebopha ngqo ku-sFlt-1. Le molekyuli ifakwe kudivayisi yokuhlunga igazi, ukuze, ngenqubo ye i-extracorporeal apheresis (njengokufana nokuhlanza izinso), kungenzeka ukudlulisa igazi likamama ohlelweni bese kususwa i-sFlt-1 eningi ngaphandle kokushintsha ezinye izingxenye ezibalulekile.
Esifundweni sokuqala kwabesifazane abangu-16 abane-preeclampsia embi kakhulu ekuqaleni, umfutho wegazi ubonise ukuthi ukuthuthukiswa okuphawulekayoAma-fetus aqhubeka nokukhula ngendlela evamile, futhi ukukhulelwa kwaqhubeka isikhathi esingaphezu kwezinsuku eziyi-10, isikhathi esiphindwe kabili kunesibonwa ezigulini ezinezimpawu ezifanayo ezingazange zithole ukwelashwa. Uma kukhulunywa ngokukhula ngaphambi kwesikhathi okukhulu, izinsuku ezimbalwa ezengeziwe esibelethweni zingenza umehluko omkhulu ekubikezelweni komntwana.
Esinye isici ababhali abasigcizelelayo ukuthi, ngokungafani nezinye izindlela zokwelapha ezifaka imithi emisha emzimbeni, lolu hlelo lukhawulelwe ku- susa into eyingoziNgokwethiyori, lokhu kungaholela emiphumeleni emibi embalwa yezokwelapha, yize kusesenesikhathi kakhulu ukuthola iziphetho eziqinile. Abalobi bocwaningo baphawula ukuthi leli isu lokuhlola elidinga izivivinyo ezinkulu zezokwelapha ngaphambi kokuba kucatshangelwe ukusetshenziswa kwalo okuvamile.
Indlela yokwelapha eSpain: ukuhlolwa, ukuqapha okujulile kanye nezinqumo ezinzima
Emsebenzini wansuku zonke wezibhedlela zaseSpain, ukuphathwa kwe-preeclampsia kuhlanganisa ukuhlolwa kusenesikhathiLokhu kuhlanganisa ukuvimbela ngemithi kwabesifazane abasengozini enkulu kanye nokuqapha eduze umama nomntwana osanda kuzalwa uma lesi sifo sesivele sibonakala. Ezinye izikhungo, njengeSan Agustín University Hospital e-Avilés, zisebenzise izinqubo ezibanzi ezihlanganisa konke kusukela ku-trimester yokuqala kuze kube izinyanga ngemva kokubeletha.
Emasontweni okuqala okukhulelwa, ingozi yomuntu ngamunye ye-preeclampsia ibalwa ngokusekelwe kumingcele eminingana: umlando womama kanye nezici, umfutho wegazi ophakathi, i-Doppler ultrasound ye-ultrasound. imithambo yesibeletho Ku-ultrasound kanye nokunqunywa kwamaprotheni e-placental njenge-PlGF. Uma umphumela ubonisa amathuba aphezulu, i-acetylsalicylic acid inikezwa ngaphambi kwesonto le-16, njengoba ukusetshenziswa kwe-aspirin ephansi kusenesikhathi kuye kwabonakala kunciphisa ngokucacile i-preterm preeclampsia.
Uma lesi sifo sibonakala ku-trimester yesithathu, umgomo oyinhloko uba ukwandisa isikhathi sokukhulelwa ngangokunokwenzeka ngaphandle kokubeka engcupheni ukuphepha kukamama ngokungafanele. Phakathi nalesi sigaba, kusetshenziswa imithi yokwehlisa umfutho wegazi, i-magnesium sulfate yokuvimbela ukuquleka, kanye ne-corticosteroids yokusheshisa ukuvuthwa kwamaphaphu engane, kuyilapho kulindelekile isikhathi sokukhulelwa esivumela ukubeletha okungeyona ingozi kakhulu.
Uma lesi simo singaphenduli ekwelashweni kwezokwelapha noma uma kutholakala izimpawu zokuwohloka kumama noma enganeni, iqembu liyaphoqeleka ukuthi libangele ukubeletha. Njengoba ochwepheshe abahilelekile kulezi zinqumo besho, zimbalwa izimo eziyinkimbinkimbi ekubelethweni njengalokhu kulinganisela okuqhubekayo phakathi kokubeletha. ukungavuthwa ngaphambi kwesikhathi kanye nokuwohloka kukamama noma kwengane. Ekukhulelweni okungaphezu kwamasonto angu-34, ukuphathwa kwenziwa ngabanye kuze kube yisonto lama-37, lapho ibhalansi ikhomba khona ngokusobala ekubangeleni ukubeletha. Kulezi zimo, ingane esanda kuzalwa ingadinga ukuhlala isikhathi eside emayunithi ezinsana ezisanda kuzalwa kanye nokunakekelwa okukhethekile.
Ngesikhathi esifanayo, ezinye izibhedlela ezihamba phambili zikhuthaza amayunithi athile e- izindlela zokubeletha eziyingozi kakhulu lapho odokotela bezifo zabesifazane, odokotela bezifo ze-nephrologist kanye nabanye ochwepheshe besebenza ngendlela ehlelekile ukuze babhekane hhayi kuphela nesigaba esibi salesi sifo, kodwa nemiphumela yaso yesikhathi esimaphakathi neside, ikakhulukazi ezinso kanye nasesimisweni senhliziyo nemithambo yegazi.
"I-trimester yesine": imiphumela ye-preeclampsia ngemva kokubeletha
Nakuba ezimweni eziningi izimpawu ze-preeclampsia ziphela ngemva kokubeletha, inkinga ayipheli ngokukhishwa kwe-placenta. Kuvamile ukuthi kube nezinkinga. izinkinga zangemva kokubelethaikakhulukazi emasontweni ambalwa okuqala, yingakho ochwepheshe bencoma ukuqapha eduze ngisho nangemva kokuphuma esibhedlela. Kukhona ngisho namacala abikiwe okutheleleka. i-preeclampsia ngemuva kokubeletha okubonisa isidingo sokunakekelwa kwangemva kokubeletha.
Amanye amaqembu eSpain asevele ekhuluma ngalokho okubizwa ngokuthi "ikota yesine" Lokhu kubhekisela esikhathini esibucayi sangemva kokubeletha. Kubhekwa njengesikhathi esifanele sokubukeza ngokugcwele umthelela we-preeclampsia emzimbeni kamama nokuthola izimo ezinjengokwehluleka kwezinso okuqhubekayo, umfutho wegazi ophakeme okunzima ukuwulawula, noma izinkinga zokuqina kwamalungu omzimba. Ngokwesibonelo, e-Asturias, odokotela bezifo ze-nephrologists kanye nodokotela bezifo zokubelethisa babambisana ekubonisaneni okuhlangene ukuze bahlole ngokuphelele isimo salezi ziguli.
Kunconywa ukwenza ukuhlolwa okuthile ekupheleni kwethemu yesine kanye nokunye okuphathelene izinyanga eziyisithupha ngemuva kokubelethaNgaphambi kwalolo suku, ezinye izinguquko zingase zibe umphumela oqondile wokukhulelwa. Lokhu kuhlolwa kuhlaziya imingcele efana ne-cholesterol, ushukela, isisindo somzimba, kanye nokusebenza kwezinso, ngenhloso yokusungula izindlela zokuvimbela kwabesifazane abasebasha kodwa asebevele besengozini enkulu yokuba nenhliziyo nemithambo yegazi.
Ngemva konyaka wokuqala, ukulandelwa kuvame ukuthathwa ukunakekelwa okuyisisekelo, yize ochwepheshe begcizelela ukuthi noma yimuphi owesifazane oye wahlupheka i-preeclampsia noma umfutho wegazi ophakeme wokukhulelwa Kufanele wazise udokotela wakho ukuze lo mlando ucatshangelwe lapho uhlola ingozi yakho yesikhathi esizayo yokuhlaselwa yinhliziyo, unhlangothi, noma isifo sezinso esingamahlalakhona.
Umthelela ezinganeni: impilo yenhliziyo iqala ekukhulelweni
Ucwaningo lwamuva luqokomisa ukuthi izinkinga zomfutho wegazi ophakeme zokukhulelwa azishiyi nje kuphela isilonda kumama, kodwa zingathinta nempilo yakhe. impilo yenhliziyo yezingane Ngemva kwamashumi eminyaka. Ucwaningo lwe-Northwestern Medicine, olwanyatheliswa ku-JAMA Network Open, lulandele cishe abantu abangu-1.350 abazalwa ngomama nezingane kusukela ekuzalweni kuze kube yilapho sebekhulile.
Lapho kuhlaziywa izingane ezineminyaka engaba ngu-22, kwaphawulwa ukuthi lezo ezinonina ababeziveze umfutho wegazi ophezulu, i-preeclampsia noma i-eclampsia Ngesikhathi sokukhulelwa, babonise, ngokwesilinganiso, inkomba ephezulu yesisindo somzimba, umfutho wegazi ophakeme we-diastolic, amazinga kashukela egazini aphakeme kancane, kanye nezimpawu zokujiya kwezindonga zemithambo ye-carotid, ukubonakaliswa kokuqala komonakalo wemithambo yegazi.
Nakuba umehluko ungase ubonakale umncane ekuqaleni, abacwaningi bawuchaza njengolingana neminyaka eminingana "ukuguga kwemithambo yegazi okuthuthukile"Ngaphezu kwalokho, ezinye izinkinga ezifana nesifo sikashukela sokukhulelwa noma ukuzalwa ngaphambi kwesikhathi nazo zihlotshaniswa noshintsho ekucindezelweni kwegazi noma ekugayweni kweglucose ezinganeni.
Lokhu okutholakele kusekela umbono wokuthi ingozi ye-cardiometabolic ingadluliselwa kusuka kwesinye isizukulwane kuya kwesinye ngokuhlanganiswa kwe- izici zebhayoloji, ezemvelo, kanye nokuziphathaUkunakekela impilo yenhliziyo nemithambo yegazi kusukela ebuntwaneni nasebusheni, ukugwema ugwayi, ukugcina ukudla okunempilo, ukulala kahle nokuzivocavoca njalo akugcini nje ngokuzuzisa umuntu ngamunye, kodwa kunganikeza izingane zabo zesikhathi esizayo “ifa” elingcono ngokwempilo.
Ukuvimbela: ukuhlolwa kwangaphambi kokubeletha, i-aspirin, kanye nendlela yokuphila
Uma kukhona umyalezo owodwa ovumelana ngawo odokotela bezifo zabesifazane, odokotela bezinzwa, kanye nodokotela benhliziyo, ukuthi ukuvimbela kuqala nge- ukunakekelwa kwangaphambi kokubeletha futhi njalo. Ukuya kudokotela ngokushesha nje lapho ukukhulelwa sekuqinisekisiwe kuvumela ukuhlonza abesifazane abasengozini enkulu kusukela ekuqaleni kanye nokusetshenziswa kwamasu okuvimbela afanelana nesimo ngasinye.
Kwabesifazane abakhulelwe abasengozini enkulu, iziqondiso zemitholampilo zincoma ukuphathwa kwe- imithi yokuvimbelanjenge-aspirin ephansi, lapho iqalwa ngaphambi kwesonto le-16. Ubufakazi obutholakalayo busikisela ukuthi lesi sinyathelo singanciphisa kakhulu ukuvela kwe-preeclampsia yokuqala, okuvame ukudinga ukubeletha ngaphambi kwesikhathi.
Ukudla okunempilo kudlala indima eqashelwa kakhulu. Ukugcina iphethini yokudla enempilo ngesikhathi sokukhulelwa kubalulekile. Ukudla kwaseMeditheraUkunciphisa ukudla okucutshungulwe kakhulu ngangokunokwenzeka kungasiza ekunciphiseni ingozi yomfutho wegazi ophakeme kanye nezinkinga ze-metabolic. Ngokufanayo, ukulawula ukukhuluphala, ukugwema ukubhema, ukunciphisa ukudla usawoti, kanye nokuzibandakanya emisebenzini yomzimba efanele ukukhulelwa kuyingxenye yezincomo ezivamile.
Esinye isici esibalulekile yi- imfundo yezempiloImikhankaso yokuqwashisa, izifundo, kanye nezinkulumo ezihloselwe abesifazane abakhulelwe zifuna ukubafundisa ngezimpawu eziyisixwayiso ze-preeclampsia kanye nokubaluleka kokungazilungisi izimpawu ezifana nobuhlungu obukhulu bekhanda, ukubona okufiphele, noma ukuvuvukala okukhulu. Ukwazi ukuthi kufanele uye nini egumbini lezimo eziphuthumayo kungenza umehluko phakathi kokwesaba nenkinga enkulu.
Kulesi simo, izinhlangano eziyisisekelo kanye nezinhlangano zisebenzisana nezinhlelo zezempilo ukuqinisa ukuqeqeshwa kwabasebenzi kanye nezinqubo zokwenza izinto lapho bebhekene nobunzima. izifo ze-hypertensive zokukhulelwaUkuqaliswa kwamakhodi athile ezimo eziphuthumayo kanye nokuvuselelwa njalo kwemishini yokunakekelwa kwempilo kusiza ekuthuthukiseni impendulo ezimweni ezimbi kakhulu.
Yonke le mizamo ehlanganyelwe, kusukela ocwaningweni oluyisisekelo ngamaprotheni e-placenta kuya kumadivayisi amasha okuhlola, ingakhohlwa umsebenzi wezibhedlela nsuku zonke kanye nemfundo yabesifazane abakhulelwe, ikhomba emgomweni ofanayo: ukuthi i-preeclampsia ayibe yisongo esithule futhi iba yinkinga engalawuleki, ngokufa okuncane komama nokubeletha kanye nekusasa elinempilo kokubili komama nezingane zabo.
