Inkampani ye-biotech yaseValencia i-iPremom ithole ama-euro ayizigidi ezingu-15 ukusheshisa ukuqaliswa kwepulatifomu yayo yokuxilonga ama-molecule eyenzelwe ukuthola izinkinga zokukhulelwa kusenesikhathi. Le nkampani esePaterna, isiqede umjikelezo wokuxhaswa ngemali ngokubambisana nabatshalizimali bamazwe ngamazwe nabaseSpain, ihlose ukwenza ukuhlolwa kwegazi kube ithuluzi elijwayelekile emitholampilo yabesifazane.
Lo msebenzi, osekuphele iminyaka engaphezu kweyishumi usungulwa, usekelwe ekutholeni izimpawu zama-molecule egazini likamama ezivela esikhathini eside ngaphambi kokuba izimpawu zomtholampilo zibonakale. Lokhu kuvumela abacwaningi ukuthi babikezele ingozi ye- preeclampsia, enye yezinkinga zokukhulelwa ezesatshwa kakhulu, kanye nezinye izinkinga ezinjengokuzalwa ngaphambi kwesikhathi noma isifo sikashukela sokukhulelwa.
Ukuthuthukiswa kwezezimali ukuze kuqinisekiswe umtholampilo
Umjikelezo wokuxhaswa ngezimali uholwa yinkampani yaseBrithani i-Amadeus Capital Partners, kanye nenkampani yaseSpain i-Asabys njengomholi ohlangene ngesikhwama sayo seSabadell Asabys II. I-APEX Ventures nayo ihlanganyele. Ngalezi zimali, i-iPremom ihlela ukuqedela ukuqinisekiswa kwezokwelapha kokuhlolwa kwayo kwe-MaiRa futhi ilungiselele ukuvunyelwa komthetho eYurophu nase-United States . Ipulatifomu isivele itholakala eSpain ngenxa yelabhorethri yenkampani uqobo.
Ngokusho kwenkampani, uxhaso luzobavumela futhi ukuthi bandise ithimba labo lokuphatha futhi bandise umthamo wokukhiqiza, okuyisinyathelo esidingekayo ukuze izibhedlela nezikhungo zezempilo ziqalise ukuhlolwa kalula. Akuyona nje indaba yobuchwepheshe: badinga ukukhombisa ukuthi isebenza ngaphansi kwezimo zangempela nokuthi ukusetshenziswa kwayo kuyasebenza ohlelweni lwezempilo.
KuDkt. Carlos Simón, umsunguli kanye nomongameli we-iPremom, lolu xhaso luyingqophamlando ebalulekile. “Ezizukulwaneni ngezizukulwane, izinkinga eziningi zokukhulelwa azizange zihlolwe kahle futhi azizange ziphathwe kahle ,” uphawula, enezela ngokuthi umgomo ukunikeza wonke owesifazane okhulelwe umbono wokuqala nophelele wokukhulelwa kwakhe.
I-MaiRa: Lena indlela ukuhlolwa okuhlaziya i-RNA egazini likamama okusebenza ngayo
Ubuchwepheshe be-iPremom busekelwe ekuhlaziyweni kwe-RNA engenamaseli ajikelezayo (cfRNA) etholakala kusampula yegazi elilula elivela kumama. Le RNA iqukethe ulwazi mayelana nezinqubo zebhayoloji ezenzeka ku-placenta kanye ne-endometrium, futhi ingaveza izinguquko ezihlobene nezinkinga ezifana ne-preeclampsia, ngisho naphakathi kwamasonto angu-9 no-14 okukhulelwa.
Le nqubo ihilela ukukhipha i-RNA nokusebenzisa imodeli yokubikezela eyenziwe ngobuhlakani bokwenziwa. Ngokusho kwenkampani, amasampula angaphezu kuka-26.000 avela ekukhulelweni okungaba ngu-10.000 asecutshungulwe , okunikeza isisekelo esiqinile sokuqeqesha ama-algorithms. Ucwaningo lwezokwelapha, olubizwa ngokuthi i-PREMOM, lungolunye olukhulu kakhulu lohlobo lwalo olwenziwe eSpain.
Kwabochwepheshe bezempilo, inzuzo isobala: esikhundleni sokuhlanganisa izici eziningana (umlando wezokwelapha, i-ultrasound, ukulinganisa umfutho wegazi, ukuhlaziywa kwezinye izakhi zofuzo), isilinganiso sengozi singatholakala ngokuhlolwa kwegazi okukodwa . Lokhu kuvumela ukuqapha komuntu siqu futhi, uma kudingeka, ukungenelela kwangaphambi kwesikhathi.
Ukusekelwa kwesayensi kanye nokwanda kwezinye izinkinga
Umsebenzi kaCarlos Simón emkhakheni wokusiza ekuzaleni uyaziwa kakhulu: wasungula imitholampilo ye-IVI kanye nelebhu ye-Igenomix, eyathengiswa ku-Vitrolife ngemali engaphezu kwe-€1.000 billion. Kanye noDkt. Tamara Garrido, umqondisi wesayensi, uhole izifundo ezithole lezi zimpawu zama-molecule. UDavid Jiménez naye uhlanganyele neCarlos Simón Foundation, ehole olunye lwalolu cwaningo.
UGuillermo Ferrando Huertas, i-CEO yamanje ye-iPremom, uzobhekana nenselele yokuletha lobu buchwepheshe emakethe. Futhi hhayi lokho kuphela: inhloso ukwandisa ipulatifomu ukuze, esikhathini esizayo, isetshenziswe ukuthola ezinye izinkinga ezivamile njengokuvinjelwa kokukhula kombungu, isifo sikashukela sokukhulelwa, kanye nokuzalwa ngaphambi kwesikhathi. Lokhu kokugcina, isibonelo, okwamanje akunaso isivivinyo esithile sokubikezela , esivula insimu enkulu yamathuba.
Idatha eqoqwe yinkampani iyathandeka: minyaka yonke kuba nokufa komama abangaba ngu-260.000 , cishe izingane ezizalwa zishonile eziyizigidi ezimbili ngemva kwamasonto angu-28, kanye nokufa kwezinsana eziyizigidi ezingu-2,3 ngenyanga yokuqala yokuphila. I-Preeclampsia ithinta u-5-8% wokukhulelwa emhlabeni jikelele. Ukutholakala kusenesikhathi kwabesifazane abakhulelwe abasengozini yokuthola i-HELLP syndrome noma i-preeclampsia kunganciphisa lezi zibalo.
Ngalo mjikelezo wokuxhaswa ngemali ongu-€15 million, i-iPremom izibeka endaweni yayo yokuba ngumdlali obalulekile ekuxilongweni kwangaphambi kokubeletha. Ukuhlolwa kwe-MaiRa sekuvele kuyatholakala eSpain, futhi izinyathelo ezilandelayo zihilela ukuqinisekisa ukusetshenziswa kwayo kwamanye amazwe aseYurophu nase-United States. Ukuhlanganiswa kwegazi likamama, ubuhlakani bokwenziwa, kanye neminyaka eyishumi yocwaningo kungashintsha indlela okuphathwa ngayo ukukhulelwa okuyingozi kakhulu , futhi zonke izinkomba zisikisela ukuthi ukulinda kuzoba usizo.