Una Ingane yase-Andalusia enesifo sofuzo esingavamile kakhulu Uthuthelwe eLondon esuka eSeville ukuze ayofakelwa i-thymus, inqubo eyinkimbinkimbi kakhulu eyenziwa ezikhungweni ezimbili kuphela emhlabeni jikelele. Lo msebenzi, ohlose ukwakha kabusha isimiso sakhe somzimba sokuzivikela esingekho nhlobo, unikeza ithemba elincane ngokusinda kwakhe isikhathi eside.
El Isibhedlela Universitario Virgen del RocÃo Isibhedlela sesithathe ukuxilongwa, ukulungiselela ukwelashwa, kanye nazo zonke izinto ezidingekayo zokudluliselwa kwamanye amazwe, sisebenzisana neGreat Ormond Street Hospital eLondon nezinye izikhungo zaseSpain. Leli cala seliyisibonelo sendlela ukubambisana phakathi kochwepheshe kanye nokubamba iqhaza kumanethiwekhi ocwaningo aseYurophu okwenza kube nokwenzeka ukunikeza ukwelashwa okwakungatholakali kuze kube muva nje.
Isifo sofuzo esingavamile esishiya umntwana engenakuzivikela
Intombazane iyahlupheka I-CHARGE syndrome, eyaziwa nangokuthi i-CHARGE syndrome, isifo esingavamile sofuzo esibonakala ngokukhubazeka okuningi kokuzalwa futhi, ezimweni zaso ezimbi kakhulu, ukungabikho kwe-thymus kanye nokuntuleka okuphelele kwama-T lymphocyte. Lesi sitho, esitholakala maphakathi nesifuba, ngemuva kwe-sternum, sibalulekile ukuze isimiso somzimba sokuzivikela sikhule futhi sivikele umzimba ezifweni.
Kulezi zimo, i- Ushintsho lwe-immunological lubi kakhulu....kuze kube sezingeni lokubeka impilo yezinsana engozini enkulu. Ngaphandle kwenani elanele lama-T lymphocyte asebenzayo, noma yikuphi ukutheleleka okuvamile kungaba yisimo esisongela ukuphila, ikakhulukazi ezinyangeni zokuqala zokuphila, lapho umzimba usengozini enkulu.
Ochwepheshe baseVirgen del RocÃo, ngokubambisana nochwepheshe base Isibhedlela iJuan Ramón Jiménez saseHuelvaBathole isithombe somtholampilo futhi baqinisekisa ukutholakala kwe-CHARGE syndrome ngokungabikho kwe-thymus kanye nokungabikho ngokuphelele kwama-T lymphocyte. Lo msebenzi wokuqala wokuthola, ukuzinza kanye nocwaningo lwezakhi zofuzo waba yisihluthulelo sokukwazi ukukhetha ukufakelwa i-thymus njengendlela ehlukile engokoqobo.
Ngokusho kwamaqembu e- I-Immunology Yezingane kanye nezifo ezithelelanayo, Ingane yayisengozini enkulu kakhulu yokutheleleka okukhulu Kusukela ekuzalweni, ukuhlukaniswa okuqinile kanye nezinyathelo zokuzivikela zazigcinwa. Umgomo kwakuwukuthola isikhathi nokumgcina esesimweni esihle kakhulu kuze kube yilapho edluliselwa futhi ehlinzwa phesheya kwezilwandle.
Ukufakelwa okuyingqayizivele okwenziwa ezibhedlela ezimbili kuphela emhlabeni.
Okwamanje, i ukufakelwa kwe-thymus Kuyindlela ekhethekile kakhulu eyenziwa ezibhedlela ezimbili ezidumile emhlabeni wonke: iGreat Ormond Street Hospital eLondon (e-United Kingdom) kanye neDuke University e-United States. Asikho isikhungo eSpain esenza lolu hlobo lwenqubo, okudinga ukuthi iziguli zidluliselwe kwamanye amazwe.
Omncane usephenduke isiguli sokuqala sase-Andalusia kanye nowesifazane waseSpain wesibili othunyelwe eLondon ukuze athole lolu hlobo lokwelashwa. Inqubo yenziwa ngoMashi 13, 2026, eLondon Children's Hospital, esinye sezikhungo ezinolwazi oluningi kule ndlela. Ngokusho kolwazi olunikezwe yiVirgen del RocÃo Hospital, ukuhlinzwa kwenziwa ngaphandle kwezinkinga.
Ukufakelwa kuqukethe faka izicubu ze-thymic ezivela kumnikeli ophilayoIzicubu sezicutshungulwe futhi zakhuliswa ngaphambilini ngaphansi kwezimo ezilawulwayo. Uma sezitshalwe kabusha, lezi zicubu kumele zihlangane futhi ziqale ukukhiqiza ama-T lymphocyte asebenzayo, okuvumela umzimba wentombazane ukuthi wakhe uhlelo lokuzivikela olukwazi ukulwa namagciwane, amabhaktheriya, nezinye izifo.
Ngemva kokuhlinzwa, isiguli sahlala esibhedlela eLondon amasonto amaningana ukuqinisekisa ukuthi sizinzile futhi sigweme izinkinga ezisheshayo. Ngomhlaka-19 Ephreli, ngemuva kokuhlola ukuthi isimo saso sasisesimweni esihle. kuzinzile ngokwemitholampilo futhi kunezimo ezinhleUkubuyela kwakhe eSeville kwavunyelwa ukuthi aqhubeke nokuqapha esibhedlela sakhe esibhekisela kuso.
Izinyanga zomsebenzi wokuthutha okuyinkimbinkimbi kakhulu kwamanye amazwe
Ukuhlelwa kwaleli cala kudinge izinyanga zokulungiselela ezokwelapha kanye nezokuthutha yiSibhedlela saseVirgen del RocÃo University. Akukhona nje ukuthola indawo esikhungweni sangaphandle, kodwa futhi nokugcina isiguli sizinzile, ukuxhumanisa izimvume, ukuphatha amadokhumenti ezokwelapha, ukuqinisekisa ukuthuthwa okwanele, kanye nokuvumelana ngezinqubo nethimba elimukelayo.
Izinsizakalo ezivela ku- I-Neonatology, Ukunakekelwa Okujulile Kwezingane, I-Immunology Yezingane, Izifo Ezithelelanayo, I-Gastroenterology Yezingane, I-Cardiology, Ukuhlinzwa Kwenhliziyo Nesifuba, I-Physiotherapy Ukunakekelwa Kwe-Palliative kanye nezinye izinto ezikhethekile. Indawo ngayinye ibe nendima ethile, kusukela ekugcineni ukusebenza kokuphefumula kanye nokusebenza kwenhliziyo kuya ekulungiseni imithi kanye nezinyathelo zokusekela ukunciphisa ingozi yokutheleleka.
Ukudluliselwa eLondon kwenziwa ngendlela izindiza zezokwelaphaukulungele ukusingatha noma yiziphi izinkinga ngesikhathi sohambo kanye izinyathelo zokuzihlukanisa eziqinisiwe ukuvikela ingane ezifweni zokuphefumula ezingaba khona. Kwagcinwa ukubambisana okuseduze neGreat Ormond Street Hospital, kwabelwana ngolwazi oluningiliziwe lwezokwelapha futhi kwachazwa kusenesikhathi izinyathelo okufanele zithathwe lapho ifika.
Leli zinga lokuxhumana kwezempilo alibandakanyi nje kuphela amaqembu emitholampilo, kodwa futhi namayunithi okuphatha, izinsizakalo zokuthutha zezokwelapha, iziphathimandla zezempilo kanye, vele, umndeni wesiguli, okuye kwadingeka ukuthi ibhekane nenqubo eyinkimbinkimbi ngokombono wemizwa kanye nowenhlangano.
Indima yeVirgen del RocÃo kanye namanethiwekhi aseYurophu
Leli cala ligqamise Indima ehlukile yeSibhedlela saseNyuvesi i-Virgen del RocÃo ekuphathweni kwezifo eziyinkimbinkimbi nezingavamile kakhulu eSpain. Akusikho okokuqala lesi sikhungo sihlanganisa izinqubo ezikhethekile kakhulu, kodwa singesinye sezibonelo eziphawuleka kakhulu ngenxa yokuntuleka kwezibhedlela emhlabeni wonke ezingenza lolu hlobo lokufakelwa.
Ukuze kutholakale isiguli esizongenela ukhetho futhi sisisekele kuze kube yilapho kungenelelwa, kubalulekile ukuba naso amaqembu akhethekile kakhuluBajwayelene nezincwadi zesayensi zomhlaba wonke futhi banokufinyelela eziqondisweni zakamuva zezokwelapha. Ochwepheshe eSeville baxhumana njalo nezinye izikhungo zaseYurophu futhi bayingxenye yamanethiwekhi ocwaningo ezifweni ezingavamile ze-immunological, okwenza kube lula ukushintshana ngolwazi kanye nokudluliselwa kwamacala angavamile.
Ngaphezu kwalokho, ukusebenza kwe izifunda zokudlulisela nezokwelashwa zomhlaba wonke Lokhu kube yinto ebalulekile. Uma inqubo ingenakukwenziwa eSpain, isibhedlela kumele sixhumane neNational Health System, iziphathimandla ezifanele, kanye nesikhungo sendawo yokuya phesheya ukuqinisekisa ukuthi ukudluliselwa kwenziwa ngaphansi kwezimo ezingcono kakhulu kanye nokuxhaswa ngemali okwanele.
I-Virgen del RocÃo igcizelele ukuthi izibonelo ezinjengalezi zibonisa indlela ucwaningo olubambisene kanye nokubambisana phakathi kwezibhedlela Bangaguqula isimo sezifo, eminyakeni embalwa edlule, ezazinobude besikhathi sokuphila obulinganiselwe kakhulu. Ngakho-ke, ukufinyelela ekwelashweni okusha kwamanye amazwe kuba yingxenye yezindlela zokwelapha ezitholakalayo ezigulini zaseSpain ezinezifo ezingavamile kakhulu.
Ukubuyela eSeville nokuqapha ngokucophelela ukuvuselelwa kwamasosha omzimba
Ngemva kokubuyela kwakhe eSeville ngo-Ephreli 19, umntwana wangeniswa esibhedlela i- Isibhedlela Sezingane sase-Virgen del RocÃolapho ahlala khona eqashwe izinsuku ezimbalwa. Odokotela babike ukuthi intuthuko yakhe ibe yinhle, ngaphandle kwezehlakalo ezimbi kakhulu, nokuthi isimo sempilo sentombazane sibhekwa njengesizinzile, okwamenza wakhishwa esibhedlela ekupheleni kwaleyo nyanga efanayo.
Kodwa-ke, umsebenzi awukapheli. Manje kuqala isigaba esibucayi kakhulu: ukuvuselelwa kwamasosha omzimbaLe nqubo, ezohlala phakathi kwezinyanga eziyisithupha neshumi nambili, yisikhathi esidingekayo ukuqinisekisa ukuthi izicubu ze-thymic ezitshaliwe ziyasebenza nokuthi umzimba uqala ukukhiqiza ama-T lymphocyte ngobuningi nangekhwalithi eyanele.
Phakathi nalesi sikhathi, ithimba le-Pediatric Immunology kanye nezinye izazi ezikhethekile ezihilelekile zizokwenza ukuqapha okuqinile ngezikhathi ezithile. ukuhlolwa okuqondile kokulinganisa ama-T lymphocyteUkuhlolwa kokusebenza komzimba kanye nokuhlolwa okuphelele kwemitholampilo ukuthola noma yiziphi izimpawu zokwenqatshwa, ukutheleleka, noma izinkinga ezihlobene nokufakelwa isitho ngokushesha.
Njengengxenye yalokhu kuqapha, i-biopsy ye-thymus etshalwe kabusha eSibhedlela saseVirgen del RocÃo University uqobo. Ithimba lokuhlinzwa elivela esibhedlela saseLondon lizohlanganyela kule nqubo, liye eSeville ukuyosebenzisana nochwepheshe eSibhedlela Sezingane, okuqinisa ukubambisana kwamazwe ngamazwe ngesikhathi esibalulekile ekululameni kwesiguli.
Kuyo yonke le nyanga, intombazane izohlala ekhaya ngaphansi kokubhekwa okuseduze kakhulu futhi inezincomo eziqinile zokuvimbela ukutheleleka. Noma yikuphi ukutheleleka okuncane kungahlala kuyinkinga enkulu ngenkathi amasosha omzimba wayo esalulama, ngakho-ke ukubambisana phakathi komndeni nethimba lezokwelapha izobaluleka.
Leli cala libonisa ukuthi kanjani, ngenxa ukukhethekile kwezokwelapha, ukuxhumanisa imikhakha eminingi, kanye nezivumelwano zomhlaba wonkeIngane enesifo esibi kakhulu sokuzivikela komzimba ithole ukufakelwa i-thymus, inqubo eyenziwa ezikhungweni ezimbili kuphela emhlabeni jikelele. Inselele manje ukuthi izicubu ezifakwe kabusha zibambe futhi zivumele ukuthuthukiswa kwesistimu yokuzivikela yomzimba efanelekile, umgomo ozoqashwa eduze yiSeville ngokubambisana neLondon.
