Ingane ingabhekana nengozi eyengeziwe yokukhula asma uma umama wakho ezwa ukucindezeleka ngesikhathi sokukhulelwa, ikakhulukazi uma esebenzisa imishanguzo yokulwa nengcindezi. Lokhu kushiwo ngucwaningo lwamuva olwenziwe e-University of Aarhus eDenmark.
Kodwa-ke, bangaphezu kuka-80% abesifazane abasesifundweni abathathe imishanguzo yokulwa nengcindezi ekilasini elisha lemithi eyaziwa ngokuthi i-serotonin reuptake inhibitors ekhethiwe (SSRIs) abakhombisanga ubungozi bokwanda kwesifuba somoya enganeni. Ngizokutshela konke ngalesi sifundo esingezansi.
"Ukuthi ukucindezeleka komama kuyithinta kanjani ingozi yokuba nesifuba somoya ezinganeni kungaziwa, kodwa indlela esebenza ngayo ingabandakanya ukushintsha kwamahomoni noma ushintsho ezindleleni zokuphila", kusho umbhali oholayo walolu cwaningo, uDkt. Xiaoqing Liu. "Okutholakele okubaluleke kakhulu ocwaningweni lwethu ukuthi sithole ukuthi ukusetshenziswa kwezidambisi zempilo ngesikhathi sokukhulelwa akubunyusi ubungozi be-asthma ngokujwayelekile."
Kodwa-ke, inkinga yehlukile lapho abacwaningi babheka kuphela ifayili le- imishanguzo emidala, eyaziwa njenge-anti-depressants ama-tricyclics. Bathola ukuthi le mithi ixhunywe ezingeni elifanayo lobungozi obukhulayo be-asthma njengokucindezeleka ngesikhathi sokukhulelwa, ngokusho kwabaphenyi. Ocwaningweni, babalelwa ku-8% abesifazane abathathe imishanguzo emidala kunayo yonke.
Ukucindezeleka kuthinta phakathi kwabesifazane abakhulelwe abaphakathi kuka-7 no-13%ngokolwazi lwangemuva ocwaningweni, nokusetshenziswa kwezidambisi zempilo ngesikhathi sokukhulelwa kuye kwanda eminyakeni yamuva. Ama-SSRIs yimithi ejwayelekile kakhulu ebekiwe yokudangala.
U-Liu nethimba lakhe bahlaziya amarekhodi ezokwelapha ezingaphezulu kwezingane ezingama-733.000 zaseDenmark ezizalwe phakathi kuka-1996 no-2007. Bangaphezu kuka-21.000 omama okungenzeka ukuthi bathola ukuthi banengcindezi noma bathola incwadi kadokotela yezidambisamagciwane ngenkathi bekhulelwe.
Izingane ezizalwa omama abanokucindezeleka zinamathuba angama-25% okuthuthuka isifuba somoya sobuntwana, ngokwemiphumela yocwaningo.
Phakathi kwezingane ezicishe zibe yi-9.000 ezinikezwe omama bazo imishanguzo ngesikhathi sokukhulelwa, izingane zabesifazane abathole imishanguzo emidala kunayo yonke yokuba nengcindezi zinengozi engama-26% yokuthola isifo somoya.
Ucwaningo alufakazeli ukuthi ama-anti-depressants amadala andise ingozi yesifuba somoya, kuphela ukuthi bekukhona ukuhlangana phakathi kwalaba ababili. Abaphenyi baqaphele ukuthi ama-tricyclic antidepressants anqunyelwe ukucindezeleka okukhulu kakhulu, obekuvele kuxhunyaniswe nesifuba somoya ocwaningweni olwedlule. Ngokwengeziwe, ucwaningo luthole kuphela ubudlelwane obuphakathi kokucindezeleka nobungozi be-asthma, hhayi ubudlelwane bezimbangela nomphumela.
"I-Tricyclic anti-depressants inezakhiwo ezahlukahlukene ze-pharmacokinetic kunama-SSRI, kepha inhlangano ingaphoxeka ngenxa yengcindezi enkulu," Kusho uLiu.
Ngamanye amagama, kungahle kube ukuthi isizathu sengozi eyandayo yesifuba somoya ukuthi omama abathatha imishanguzo ye-tricyclic sebenengcindezelo enkulu kakhulu nokuthi ukucindezeleka, hhayi izidakamizwa, okufaka engcupheni yesifuba somoya.
Akucaci nokho ukuthi ukucindezeleka kukamama kungaletha kanjani engozini yengane yesifuba somoya. Isixhumanisi singachazwa ngokwengxenye yi-biology, ngokuthile okwenzeka ngesikhathi sokukhulelwa, ngokubandakanya izici zemvelo noma zofuzo, noma bobathathu, kuchaze uLiu.
"Abaphenyi baphinde bathola ukuthi ukudana kwengqondo kubazali kuyayinyusa kancane ingozi yokuba nesifuba somoya, bephakamisa ukuthi uhlobo oluthile lwezici zemvelo noma zofuzo lungabandakanyeka ezinganeni," Kusho uLiu.
Udokotela UJill rabin, ongudokotela obelethayo nodokotela wezifo zabesifazane onezinsizakalo zezeMpilo eNorth Shore-LIJ Health System eNew Hyde Park, eNew York, uphawule ngalolu cwaningo ukuthi noma yisiphi isifundo esihle siphakamisa imibuzo eminingi kunezimpendulo.
"Uma unomzali ocindezelekile, ngabe isimo sasekhaya sinombango othinta wonke umndeni?"Kubuza uRabin. «Ngabe ithoni yezenhlalo nezingokomzwelo yendlu ithinta impilo yokuphefumula kwengane? Kungenzeka yini ukuthi abazali kule ndlu abacindezelekile bayabhema? "
Ababhali bezocwaningo balungisa imiphumela yabo ukuze babhekele omama ababebhema ngesikhathi sokukhulelwa, kepha kabazange banake ukuthi obaba babebhema noma eminye imithombo yentuthu. "Ukubhema ngesikhathi sokukhulelwa kunomthelela ekukhuleni kwamaphaphu engane", URabin waveza.
Kodwa-ke, naphezu kwalokhu kuzamazama komhlaba, uRabin uphinde wathi okutholakele ocwaningweni akufanele kushintshe isinqumo sanoma yimuphi umuntu wesifazane sokulapha ukudangala ngesikhathi ekhulelwe.
"Lolu cwaningo luphakamisa imibuzo ethokozisayo efanele ukudingidwa, kepha abukho ubufakazi bokuthi imishanguzo elwa nokudangala ibanga isifuba somoya." uthe. "Sifuna abesifazane belashelwe ukucindezeleka ukuze bakwazi ukuzisebenzela kangcono, imindeni yabo kanye nezinsana ezisanda kuzalwa."
Imiphumela yalolu cwaningo ishicilelwe ku- Pediatrics