Uma uzama ukukhulelwa, cishe uyazi yini u-Omifin Futhi ukuthi isetshenziselwani, kodwa uma ungazi, uzojabula ukuthola ngoba ingase ikunike ithemba elincane ngokuba ngumama kwakho kwesikhathi esizayo. Uma ufuna ukuba nomntwana futhi uzame konke, qhubeka ufunda ngoba i-Clomid ingakusiza ukufeza umgomo wakho futhi ukhulelwe ngokwemvelo ngaphandle kokusebenzisa ubuchwepheshe bokusiza ekuzaleni.
I-Omifin umuthi lokho Isetshenziselwa ukunqoba izinkinga ezithile zokungabi nabantwana., kepha kufanele uqale wazi ukuthi iyini nokuthi kufanele isetshenziswe kanjani ukukwazi ukuyenza kahle. Njengayo yonke imithi edliwayo emphakathini wethu, kubalulekile ukuthi udokotela wakho akwazi konke lokhu ukuze akunikeze imihlahlandlela nezeluleko ezidingekayo ukuze zisebenze kangcono.
I-Omifin yaziwa nangokuthi yiClomiphene Citrate —ungase uyiqaphele ngaleli gama— futhi ihlobene ngqo nokukhulelwa kwabesifazane abaningi. Kodwa ngaphandle kokwazi ukuthi iyini, kubaluleke kakhulu futhi ukuqaphela ukuthi kunini lapho kungafanele uyithathe ngaphansi kwanoma yiziphi izimo nokuthi yimiphi imiphumela emibi engayibangela.
I-Clomid: iyini nokuthi isebenza kanjani
I-Omifin yigama ozolibona ebhokisini lemithi futhi, njengoba ngishilo ngenhla, yaziwa nangokuthi i-clomiphene citrate ngoba yiyo leyo isimiso esisebenzayo. I-Omifin isebenza ngokukhuthaza ukuvuthwa kwamaqanda kwabesifazane abayisebenzisayo, ibanika ithuba elingcono lokukhulelwa ngokwemvelo.Kufana "nokusunduza" kowesifazane ukwenza ukuvuthwa kwakhe kube kaningi futhi kubikezelwe uma kukhona izinguquko.
Ngokombono wezokwelapha, i-clomiphene citrate iyisidakamizwa esisebenzayo. i-ovulation inducer enesenzo sokulwa ne-estrogenicLokhu kusho ukuthi ibopha kuma-receptor e-estrogen atholakala ku-hypothalamus (indawo yobuchopho elawula ama-hormone okuzala) futhi ivimbele kancane isignali ethunyelwa yi-estrogen ngokwemvelo. Ngokuvimba lesi signali, ubuchopho buchaza amazinga e-estrogen njengaphansi futhi busabela ngokwandisa ukukhishwa kwe-GnRH, okubuye kukhuthaze i-pituitary gland ukuthi ikhiphe i-estrogen eyengeziwe. I-FSH ne-LH.
Lawa ma-hormone amabili, i-FSH (i-follicle-stimulating hormone) kanye ne-LH (i-luteinizing hormone), anesibopho salokhu. ukukhuthaza ama-ovari ukuthi avuthwe futhi akhulule amaqandaNgale ndlela, i-Clomid isiza ekwakheni okungenani i-follicle eyodwa evelele futhi ikhiqize ukuvuthwa kwamaqanda, ngisho nakwabesifazane abangavuthi njalo noma abangavuthi nhlobo.
Uma ungowesifazane ovame ukubhekana nezinkinga ngomjikelezo wakho wokuvuthwa kwamaqanda, ngaphezu kokubonisana nodokotela wakho ukuthola ukuthi kwenzekani, i-Clomid (Omifin) ingaba yisisombululo esihle kuwe. Lo muthi ofanayo ubizwa ngokuthi... I-Clomid E-United States, lokhu kubalulekile ukwazi ukuthi uhlala lapho futhi ungathanda yini ukukuthatha ukuze wandise amathuba akho okukhulelwa, njengoba isithako esisebenzayo kanye nendlela esebenza ngayo kuyafana.
Ukwethulwa, umthamo ojwayelekile kanye nendlela yokuphathwa
I-Clomid iza ngesimo se- amaphilisi okuphathwa ngomlomoIthebhulethi ngayinye ivame ukuba ne 50 mg we-clomiphene citrateLona umthamo ojwayelekile wokuqala wezindlela eziningi zokwelapha inzalo. Ngaphezu kwesithako esisebenzayo, amaphilisi aqukethe izinto ezisizayo njenge-lactose, i-sucrose, isitashi sommbila, kanye ne-magnesium stearate, ngakho-ke kubalulekile ukwazisa udokotela wakho uma ubhekene nanoma yiziphi izimo ezilandelayo: ukungabekezelelani noshukela othile noma ukungezwani komzimba nanoma yiziphi izingxenye zayo.
Umthamo oqondile kanye nezinsuku ezithile zokuwuthatha kufanele kunqunywe njalo nguchwepheshe, kodwa ngokuvamile:
- La Umthamo wansuku zonke uvame ukuba phakathi kuka-50 no-100 mgOkusho ukuthi, phakathi kwephilisi elilodwa namaphilisi amabili ngosuku.
- Ukwelashwa kuvame ukuqala phakathi usuku lwesibili nolwesihlanu lomjikelezo wokuya esikhathini (kubalwa kusukela osukwini lokuqala lokuya esikhathini) futhi kuqhubeka isikhathi eside 5 izinsuku ezilandelanayo.
- Ngemva kokuqeda inkambo yamaphilisi, ukuvuthwa kwamaqanda kuvame ukwenzeka phakathi kwezinsuku ezingu-11 no-15 zomjikelezongakho udokotela ukhomba lezo zinsuku njengezinsuku ezivundile kakhulu zokuba nobuhlobo bobulili obuhleliwe.
Kwezinye izindlela zokusiza ekuzaleni, udokotela wakho wezifo zabesifazane angase akunikeze i-Clomid kuze kube usuku lapho kukhishwa khona i-ovulation ngomunye umuthi oqukethe i-hormone hCG (isibonelo, i-Ovitrelle). Kuleso simo, i-ovulation ivame ukwenzeka cishe Amahora angu-36 ngemva komjovo we-hCG.
Kubalulekile futhi ukwazi lokho Akukhuthazwa ukuthatha i-Clomid imijikelezo engaphezu kweyisithupha elandelanayo.Ngoba kusukela ngaleso sikhathi kuqhubeke, ukusebenza kahle kuvame ukwehla, futhi isidingo sokucabanga ngezinye izindlela zokwelapha siyanda. Ngakho-ke, ukuqapha kwezokwelapha kanye ne-ultrasound elandelanayo kubalulekile ukuze kunqunywe ukuthi kuqhubeke yini, kulungiswe umthamo, noma kushintshwe isu lokwelashwa.
I-Clomid iyindlela enhle kwabesifazane abaningi
Eminyakeni edlule i-Clomid ithengiswe, abesifazane abaningi bakhulelwe ngenxa yalo muthi. Odokotela abaningi bezifo zabesifazane bawunikeza abesifazane ukuze ubasize bakhulelwe ngokushesha noma baphumelele ekukhulelweni. Akungabazeki ukuthi ingenye yemithi eyaziwa kakhulu yokukhuthaza ukuvuthwa kwamaqanda futhi okudume kakhulu ngokukhulelwa ngenxa yempumelelo yayo uma iboniswe kahle.
Izifundo ezenziwa emaqenjini amakhulu eziguli zibonisa ukuthi ukusetshenziswa okufanele nokulawulwa kwe-Clomid (Omifin) Ibuyisela ukuvuthwa kwamaqanda cishe ku-70% wabesifazane. abakuthatha njengesibonakaliso esithile. Ezigulini ezine-polycystic ovary syndrome (PCOS), izinga lokuvuthwa kwamaqanda lingaba phezulu nakakhulu, okunikeza ithuba langempela lokuthola ukukhulelwa ngocansi oluhleliwe.
Noma kunjalo, kufanele kucatshangelwe ukuthi Ukukhipha amaqanda akufani nokuthola ukukhulelwaNgisho noma ukukhishwa kweqanda kutholakala nge-Clomid, amathuba okukhulelwa ngomjikelezo ngamunye aphakathi kuka-5 no-20% kuye ngeminyaka, isimo sempilo jikelele kanye nokuba khona noma ukungabikho kwezinye izinkinga zokuzala kumbhangqwana (njengokungavamile kwesidoda noma izinkinga kuma-tubes e-fallopian).
Uma ukukhulelwa kungatholakali ngemva kwemijikelezo eminingana elawulwa kahle neClomid, uchwepheshe angase atuse ezinye izindlela njengokufakelwa kwesidoda okwenziwe ngokwenziwa noma ukufakelwa kweqanda ngaphandle kokusebenzisa i-in vitro. Imbangela ethile yokungazali kufanele ihlolwe njalo ngaphambi kokuqhubeka noma ukushintsha ukwelashwa.
Ukuvuthwa kwamaqanda kwabesifazane kanye nendima yeClomid
Abesifazane abaningi abanezinkinga zokukhishwa kwamaqanda bakhetha nokuphuza i-Clomid (Omifin) ukuze balawule le nqubo. Ngesikhathi sokukhishwa kwamaqanda, owesifazane ukhipha iqanda esibelethweni sakhe ukuze likwazi ukukhulelwa yisidoda sendoda; uma lokhu kungenzeki, kuyaye kube sesikhathini. Emjikelezweni ojwayelekile, le nqubo yenzeka cishe njalo Izinsuku ze-28 Futhi uma kungekho ukukhulelwa, kuzodingeka ulinde kuze kube umjikelezo olandelayo ukuze uzame ukukhulelwa futhi.
Kulokhu, i-Omifin iyasiza ekuvuseleleni ama-ovari. I-Clomid (i-Omifin) isiza amaqanda ukuba avuthwe futhi iqinisekise izikhathi zokuzala ezithembeke kakhudlwana emjikelezweni wowesifazane. Ngaphezu kwalokho, lapho owesifazane ezama ukukhulelwa ngokwemvelo ngokusebenzisa ubuchwepheshe bokuzala obusizayo, i-Clomid ingaba ithuluzi eliwusizo lokwandisa amathuba okuphumelela, ikakhulukazi uma ihlanganiswa namanye ama-hormone athuthukisa impendulo yama-ovari.
Lokhu kungenxa yokuthi ukuthatha i-Clomid kwandisa ukukhiqizwa kwamaqanda, ngakho-ke, amathuba okukhulelwa Ngaphambilini, ezimisweni zokufakelwa kwesidoda ngokwenziwa, isibonelo, umgomo ngokuvamile ukuthola i-follicle eyodwa noma ezimbili ezivuthiwe ukunciphisa ingozi yokukhulelwa okuningi; ekukhulelisweni kwe-in vitro, i-clomiphene citrate ingahlanganiswa ne-gonadotropins ukuze kufezwe ukukhuthazwa kwama-ovari okumaphakathi.
Ngaphezu kwalokho, i-Omifin ingasetshenziswa futhi njenge- ukuhlolwa kokuxilonga Ezimweni ezithile ze-amenorrhea noma okusolwa ukuthi kunciphile i-ovarian reserve, lezi zinqubo zihilela ukunikeza umthamo othize we-clomiphene citrate izinsuku ezimbalwa ezithile zomjikelezo, kulandelwe ukuqapha amazinga e-FSH kanye ne-estradiol ukuhlola impendulo ye-ovarian.
Kukuziphi izimo lapho i-Clomid iboniswa khona?
Isibonakaliso esiyinhloko se-Clomid sikwabesifazane abahlushwa yilesi sifo. ukungazali ngenxa yokuphuma kweqanda noma ukukhishwa kweqandaOkusho ukuthi, azivuthi amaqanda noma zenze njalo ngokungajwayelekile, futhi zinamazinga ajwayelekile e-estrogen. Isibonelo esivame kakhulu yiziguli ezine- i-polycystic ovarian syndrome (PCOS)abavame ukuba nezikhathi ezingajwayelekile noma ngisho nokungabikho esikhathini kanye nobunzima bokukhulelwa ngenxa yokuntuleka kwe-ovulation.
Ngaphezu kwalokho, i-Clomid ingaboniswa kwezinye izimo ezithile, uma nje udokotela wezifo zabesifazane eyihlola kanje:
- I-amenorrhea yesibili (ukungabikho kokuya esikhathini okubonakala ngemva kokuba nemijikelezo evamile ngaphambilini), uma izimbangela ezifana ne-hyperprolactinemia, ukwehluleka kwesibeletho ngaphambi kwesikhathi noma izinkinga zomzimba sezisusiwe.
- Isigaba esifushane se-luteal (ngaphansi kwezinsuku eziyi-10): Ngokuthuthukisa ukusebenza kwe-ovulation kanye nokusebenza kwe-corpus luteum, kungasiza ekufinyeleleni amazinga e-progesterone anele akhuthaza ukufakwa kwesibeletho.
- Ubuhlobo bobulili obuhleliwe (ubulili obuhleliwe), uma ufuna ukusizakala ngesikhathi esiqondile sokuvuthwa kweqanda ukuze wandise amathuba okukhulelwa.
- Ukushushumbisa okwenziwe ngemithiukuhlela ukuvuthwa kwamaqanda nokuqinisekisa ukuthi kune-follicle eyodwa noma ezimbili ezivuthiwe ngaphambi kokufaka isidoda esibelethweni.
- Njengesengezo sokufaka umanyolo we-in vitro, kuhlanganiswe nama-gonadotropin, ukuze kutholakale ukukhuthazwa kwama-ovari okulawulwayo, ikakhulukazi kwabesifazane ababhekwa njengabanezinga eliphansi lokusabela.
Kwezinye izimo ezikhethiwe, Ingasetshenziswa futhi ekuzaleni kwabesilisa.ngoba ukwanda kwe-FSH ne-LH kukhuthaza ukukhiqizwa kwe-testosterone kanye nokukhiqizwa kwesidoda. Kodwa-ke, lokhu kusetshenziswa akuvamile futhi kudinga ukuhlolwa ngokucophelela ngudokotela we-andrologist.
Izingozi zokuthatha i-Clomid kanye nesidingo sokubhekwa kwezokwelapha
Nakuba isize abesifazane abaningi ukuthi bakhulelwe, akufanele neze uyithathe ngaphandle kwemvume kadokotela wakho kuqala. I-Clomid kufanele isetshenziswe ngaphansi kokuqondisa kukadokotela ngaso sonke isikhathi., nge-ultrasound kanye nezilawuli zokuhlaziya lapho uchwepheshe ekubona kudingekile.
Enye yezingozi ezaziwa kakhulu zokwelashwa nge-Clomid amathuba okukhulelwa okuningi (amawele, ama-triplets, njll.). Lokhu kungenxa yokuthi, lapho i-ovary ivuselelwa, ama-follicle angaphezu kweyodwa angavuthwa futhi akhulule amaqanda angaphezu kwelilodwa emjikelezweni ofanayo. Nakuba imibhangqwana eminingi ibona lokhu njengento enhle, ukukhulelwa okuningi kuhilela izingozi eziningi kumama kanye nezingane, ngakho-ke kuyinto okufanele icatshangelwe ngokucophelela.
Enye ingozi efanele yi- i-ovarian hyperstimulationUma uthatha i-Clomid (Omifin) eningi kakhulu noma uma ama-ovari akho ezwela kakhulu, ama-follicle amaningi angakhula futhi ama-ovari akho angakhula, okungaba yingozi empilweni yakho. Izimpawu zalokhu kukhuthaza okukhulu zihlanganisa ubuhlungu be-pelvic noma besisu, ukuqunjelwa, umuzwa ojwayelekile wokugcwala, kanye nokukhuluphala okusheshayo. Nakuba ukuvuselela okukhulu kakhulu kungavamile nge-Clomid, kudinga ukuyeka ukwelashwa kanye nokubhekwa eduze kwezokwelapha.
Ngakho-ke, kufanele uye kudokotela wakho, umtshele ngesifiso sakho sokuthatha i-Clomid, futhi uzokwenza ukuhlaziya okuphelele ukuthola ukuthi ungayithatha noma cha, kanye nezingozi ezingaba khona esimweni sakho esithile. Udokotela uzokutshela ukuthi kufanele uthathe umthamo ongakanani. Futhi akufanele udlule imiyalelo kadokotela wakho, ngaphandle kwalokho ungaba ne-ovarian hypertrophy engavamile (i-ovary iyakhula). Uma lokhu kwenzeka, kuzodingeka uyeke ukuthatha lo muthi kuze kube yilapho i-ovary yakho ibuyela kusayizi wayo ojwayelekile; ukuphazamiseka kokwelashwa kungathinta amathuba akho okukhulelwa, ngakho-ke ukulandela kubalulekile.
Kubalulekile ukuqonda ukuthi ukuthatha i-Clomid eningi kungabangela izinkinga. Akusho ukuthi uzokhulelwa ngokushesha.Ngokuphambene nalokho, kwandisa ingozi yemiphumela emibi kanye nezinkinga. Yingakho kubaluleke kakhulu ukulandela imiyalelo kadokotela wakho wezifo zabesifazane nokuya kuzo zonke izikhathi ezihleliwe. Ngaphambi kokuqala ukwelashwa, kuvamile ukwenza izivivinyo eziyisisekelo: ukuqinisekiswa kokukhulelwa, ukuhlaziywa kwamahomoni, kanye ne-ultrasound ye-pelvic ukuhlola ama-ovari nokukhipha ama-cyst angavimbela ukwelashwa.
Kunini lapho ungafanele uthathe i-Omifin
Kwezinye izimo kuphelele I-Omifin inqatshelwe kwabanye besifazane. Akukhonjisiwe uma kwenzeka:
- I-endometriosis ethuthukile noma engalawulwanjengoba ukukhuthazwa kwama-hormone kungenza lesi sifo sibe sibi kakhulu.
- Ama-cyst e-ovarian e-organic (azisebenzi), ngoba zinganda ngobukhulu ngokukhuthazwa.
- Ama-ovari e-Polycystic ane-hypersensitivity enkulu ku-clomiphene, uma udokotela ehlola ukuthi impendulo iphakeme ngisho nangemithamo ephansi.
- uma ukhulelweAkuvunyelwe ngokuphelele.
- Isifo sesibindi esibi noma sakamuva.
- Izinkinga ze-thyroid noma ze-adrenal ezingalashwanga.
- Ukopha kwabesifazane okungaziwa ukuthi kuvelaphi kuze kube yilapho imbangela icacisiwe.
- Izimila ezincike kuma-hormone (izinhlobo ezithile zomdlavuza ezizwela i-estrogen noma i-progesterone).
- Ukuphazamiseka kokubuka ngesikhathi sokwelashwa kwangaphambilini nge-clomiphene citrate.
- Ukungezwani komzimba noma ukusabela ngokweqile eyaziwa nge-clomiphene citrate noma ezinye zezinto ezisizayo.
Ngaphambi kokuqala ukwelashwa, udokotela kumele susa ezinye izimbangela zokungabi nabantwana Izinkinga zokuzala kwabesifazane (njengezinkinga ngamapayipi noma isibeletho) kufanele zicatshangelwe, kanye nokuzala kwabesilisa. Ukusebenzisa i-Clomid lapho imbangela yokungazali kungeyona inkinga yokukhishwa kwamaqanda akusizi nje kuphela, kodwa futhi kungandisa isikhathi kuze kutholakale ukwelashwa okufanele.
Imiphumela emibi yokuthatha i-Omifin
Njengayo yonke imithi, i-Clomid ingaba nemiphumela emibi. imiphumela emibi okufanele uyiqaphele uma kwenzeka zenzeka ngemva kokuqala ukwelashwa. Iningi lazo lincane futhi lihlala isikhathi esifushane uma usebenzisa imithamo enconywayo (50-100 mg nsuku zonke), kodwa kubalulekile ukuzazi ukuze wazi ukuthi kufanele uthintane nodokotela nini.
Ukuqinisekisa ukuthi imiphumela emibi oyitholayo ijwayelekile, kufanele ufunde ipheshana elisephaketheni bese uthintana nodokotela wakho. Uma imiphumela emibi ikhathaza kakhulu, kufanele uyeke ukwelashwa. Eminye yale miphumela emibi ihlanganisa:
- Ukuvutha okushisayo kanye nomuzwa wokushisa ngokuzumayo, ofana nalowo wokunqamuka kokuya esikhathini.
- Ubuhlungu bekhanda noma izinhlungu zekhanda ezinamandla ahlukahlukene.
- Ukuphazamiseka okubonakalayo (umbono ofiphele, ukukhanya noma amabala), okungajwayelekile kodwa kubalulekile ukuqapha.
- Ukukhuliswa kwe-Ovarian kanye nomuzwa wokusinda kwesinqe.
- Ukopha okungavamile noma ukubona phakathi kokuya esikhathini.
- Ubuhlungu besisu noma ukungakhululeki endaweni ye-pelvic.
- Isicanucanu noma ukuhlanzangokuvamile imnene.
- Ubuhlungu besifuba noma ukuthamba kwebele.
- Ukukhathazeka noma ukuphazamiseka ngokomzweloukucasuka noma ukushintshashintsha kwemizwelo.
- Ukoma kwe-Vaginal noma izinguquko ku-mucus yomlomo wesibeletho, maqondana nomphumela wayo wokulwa ne-estrogenic.
- Amarowu noma ukulunywa, okungavami njalo.
- Ukwanda kwemvamisa yomchamo kwezinye iziguli.
Ngaphezu kwalokho, nakuba kungavamile, ukusetshenziswa kwe-Clomid kungase kuhlotshaniswe nokusetshenziswa kabi kwe-hormone. i-ovarian hyperstimulation syndromeLokhu kuyiqiniso ikakhulukazi uma kusetshenziswa imithamo ephezulu noma lapho ukwelashwa kuqhubeka isikhathi esingaphezu kwesikhathi esinconywayo. Kulezi zimo, ubuhlungu obukhulu be-pelvic, ukuvuleka kwesisu okuphawulekayo, ukukhuluphala okusheshayo, ukuphelelwa umoya, noma ukugula okuvamile kungase kwenzeke. Uma kukhona okusolwayo kulezi zimpawu, xhumana nodokotela ngokushesha.
Uma uqaphela le noma eminye imiphumela engemihle ngemuva kokuqala i-Omifin, lapho-ke Kufanele ubonane nodokotela wakho ngokushesha okukhulu.Uma udokotela wakho ebona kufanele, cishe uzomisa ukwelashwa kuze kube yilapho ethola imbangela, futhi uma enza kanjalo, kuzodingeka uhlole ezinye izindlela. Ngezinye izikhathi, ukunciphisa umthamo noma ukushintsha inqubo yokukhuthaza kwanele ukuthuthukisa ukubekezelelana.
Ukuqonda ukuthi i-Clomid isebenza kanjani, uma ibonisiwe, izinzuzo zayo, kanye nezingozi ezingaba khona kukuvumela ukuthi ubhekane nokwelashwa ngokuthula kwengqondo okukhulu kanye nokuba ngokoqobo. Ngokuqondiswa okuhle kwezokwelapha, ukulindela okungokoqobo, kanye nokulalela izimpawu zomzimba wakho, lo muthi ungaba umsizi obalulekile ohambweni lwakho lokuba ngumama.